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KMID : 1094020150320020183
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Journal of Veterinary Clinics
2015 Volume.32 No. 2 p.183 ~ p.186
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Adjuvant Metronomic Chemotherapy in a Dog with Nasal Transitional Carcinoma
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Park Hyung-Jin
Kim Ja-Won
Jeong Seong-Mok
Choi Ho-Jung
Son Hwa-Young
Song Kun-Ho
Seo Kyoung-Won
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Abstract
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A four-year-old spayed female Maltese dog weighing 3 kg was referred with reverse sneezing and fourmonthhistory of unilateral nasal discharge. She was diagnosed as nasal transitional carcinoma which in bilateral nasalcavity and extending into the frontal sinus by biopsy with rhinoscopy. Metronomic chemotherapy with cyclophosphamide(12.5 mg/m2) and toceranib phosphate (2.5 mg/kg) was initiated following after surgical treatment of nasalmass debulking. Clinical response was good and had no side effects during the chemotherapy period (11 months afterdiagnosis). This is a case report describing adjuvant metronomic chemotherapy in nasal transitional carcinoma in Korea.
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KEYWORD
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cyclophosphamide, metronomic chemotherapy, nasal transitional carcinoma, surgical debulking, toceranib
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